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"Stress-induced acetylcholine signaling in the hippocampus: too much of a good thing?," by Marina Picciotto, Charles BG Murphy Professor in Psychiatry, Deputy Chair for Basic Science, Professor of Neuroscience and of Pharmacology, Yale University

Event Type
Seminar/Symposium
Sponsor
Neuroscience Program
Location
https://illinois.zoom.us/j/83566081431?pwd=VllERlduN0hrUUYzQ1p0YTk2U2xKZz09
Virtual
wifi event
Date
Nov 9, 2021   4:00 pm  
Speaker
Marina Picciotto, Yale University
Contact
Neuroscience Program
E-Mail
nsp@life.illinois.edu
Phone
217-300-7978
Views
5
Originating Calendar
Neuroscience Program Seminars

Acetylcholine (ACh) is often thought of as a neurotransmitter that is important for cognition, but we have identified increased brain ACh levels in human subjects who are actively depressed. This seminar will present data that increasing activity of ACh inputs to the hippocampus selectively induces stress-dependent behaviors, including increased susceptibility to social stress. Our working hypothesis is that ACh signaling in hippocampus may be relevant to the negative encoding bias, that is, increased focus on negative events, experienced by individuals with depression.

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