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Biochemistry Seminar: Dr. Raquel Lieberman (Georgia Institute of Technology), "How does a protein’s structure spell the difference between health and disease? Structure and misfolding of glaucoma-associated myocilin"

Event Type
Seminar/Symposium
Topics
academic, biochemistry, medicine, molecular biology
Sponsor
Sponsored by Department of Biochemistry, Dr. Satish Nair
Location
Charles G. Miller Auditorium (B102 CLSL)
Date
Oct 11, 2019   12:00 pm  
Speaker
Dr. Raquel Lieberman
Cost
Free
Contact
Sherry Unkraut
E-Mail
sunkraut@illinois.edu
Phone
217-333-2013
Views
114
Originating Calendar
Biochemistry Department Seminars

How does a protein’s structure spell the difference between health and disease? Structure and misfolding of glaucoma-associated myocilin

 

A major research effort in the Lieberman lab includes molecular investigations of myocilin, a protein implicated in the prevalent ocular disorder glaucoma. I will present our efforts toward a detailed understanding of myocilin structure and how mutations lead to glaucoma pathogenesis. Our results include striking similarities with amyloid diseases, as well as offer new targets for glaucoma therapeutics.

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