Many people who undergo surgery, experience trauma, or experience certain diseases develop pathological scar tissue that never fully disappears. In this talk, Christian Guerrero-Juarez will introduce a new multiscale systems biology approach that may be leveraged to better understand human skin conditions characterized by aberrant scarring and fibrosis. Guerrero-Juarez will discuss the identification, characterization, and functional manipulation of a micro-anatomically segregated, scar cell subset via a newly identified novel gene biomarker to revert scarring and induce regeneration. This new approach combines comparative single-cell and spatial transcriptomics with experimentation for studying mechanisms of skin regeneration in the wound-induced hair neogenesis model.
Christian Guerrero-Juarez is a third-year medical student at Carle Illinois College of Medicine at the University of Illinois, Urbana-Champaign. He earned dual bachelor’s degrees in biochemistry and biology from California State University San Bernardino and a master’s degree and doctorate in biological sciences from the University of California Irvine. His research interests include cell fate choice and cellular reprogramming during injury and disease. He is also interested in skin wound healing and regeneration, stem cells and their niche, innate immunity, patterning, and the evolution of skin appendages.
This presentation will be offered for an in-person audience only. It will not be recorded or offered virtually.
Register to join lunch in person with colleagues at MSB Lecture Hall (Room 274).
