Research Seminars @ Illinois

View Full Calendar

Tailored for undergraduate researchers, this calendar is a curated list of research seminars at the University of Illinois. Explore the diverse world of research and expand your knowledge through engaging sessions designed to inspire and enlighten.

To have your events added or removed from this calendar, please contact OUR at ugresearch@illinois.edu

STC-QCB Seminar: Markus Covert (Stanford University) "Whole-cell modeling of E. coli: from simulation to discovery"

Event Type
Seminar/Symposium
Sponsor
NSF QCB STC
Location
Beckman 3269 3rd Floor Tower Room
Date
Mar 4, 2024   3:00 - 4:00 pm  
Speaker
Markus Covert
Contact
Lisa Johnson
E-Mail
lisa3@illinois.edu
Phone
217-300-9574
Views
37
Originating Calendar
Physics - Biological Physics / iPoLS / STC-QCB Seminar

Abstract: Francis Crick first called for a coordinated worldwide scientific effort to determine a “complete solution” of the bacterium Escherichia coli. We have been working for some years now to complete a model of E. coli that takes into account all of the known functions of every well-annotated gene, in order to better understand and predict the behavior of this scientifically-relevant and industrially-significant model organism. I will discuss our ongoing efforts to improve this model, most recently with new modeling added to better describe growth rate control, transcription unit architecture and tRNA metabolism. I will then highlight our newest “whole-colony” models, a multi-scale modeling effort in which every individual within a simulated colony is running the latest version of the whole-cell model, to calculate population-level emergent behaviors based on molecular interactions and events as the colony responds to the sudden introduction of antibiotics.

link for robots only