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David Moore

The Willard J. and Priscilla F. Visek Lecture: David Moore

Event Type
Seminar/Symposium
Sponsor
College of Agricultural, Consumer and Environmental Sciences Division of Nutritional Sciences
Location
Beckman Institute Room 1025-Auditorium
Date
Oct 12, 2022   4:00 pm  
Speaker
David Moore, Professor and chair, Department of Nutritional Sciences & Toxicology, University of California Berkeley, Berkeley, California.
Contact
Angela Dean
E-Mail
aedean2@illinois.edu
Views
37
Originating Calendar
Beckman and Campus Calendars

Title: "Regulation of liver energy balance by nutrient sensing nuclear receptors"

Speaker: David Moore, Professor and chair, Department of Nutritional Sciences & Toxicology, University of California Berkeley, Berkeley, California.

The liver is crucial for maintaining whole body energy balance. For example, it responds to fasting by secreting glucose and to feeding by both metabolizing it and storing it as glycogen. The nuclear receptors FXR and PPARα are activated in the fed or fasted liver, respectively, and regulate many basic metabolic processes. Dr. Moore's lab have found that both receptors also regulate processes that are not directly related to metabolic pathways but are central to liver energy balance. Dr. Moore's presentation will focus on the previously described roles of FXR and PPARα in control of autophagy and more recent results on control of the liver secretome. 

 

 

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