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Physics Colloquium: Prediction in immune repertoires

Event Type
Seminar/Symposium
Sponsor
Department of Physics
Virtual
wifi event
Date
Dec 8, 2021   10:00 am  
Speaker
Aleksandra Walczak
Contact
Marjorie Gamel
E-Mail
mgamel@illinois.edu
Phone
217-333-3762
Views
58
Originating Calendar
Physics - Colloquium

Living systems often attempt to calculate and predict the future state of the environment.  Given the stochastic nature of many biological systems how is that possible? I will show that even a system as complicated as the immune system has reproducible outcomes. Yet predicting the future state of a complex environment requires weighing the trust in new observations against prior experiences. In this light, I will present a view of the adaptive immune system as a dynamic Bayesian machinery that updates its memory repertoire by balancing evidence from new pathogen encounters against past experience of infection to predict and prepare for future threats. 

 

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