Yi Wang, PhD
Professor, Biomedical Engineering and Radiology
Cornell University
Title: Quantitative susceptibility mapping (QSM): recent development and applications
Abstract: Tissue magnetism refers to electron–proton interaction of a long range due to the large electron magnetic moment, which contrasts with proton–proton (commonly known as spin-spin) interaction of a short range due to the weak proton magnetic moment in tissue-relaxation. The long-range magnetism implies nonlocal blooming artifacts in both magnitude (T2* weighted) and phase of gradient echo MRI signal. Quantitative susceptibility mapping (QSM) is to study magnetism by deconvolving the blooming artifacts. The Bayesian approach has been established to address the main QSM challenge, which is the ill posedness of the magnetic field to susceptibility source inverse problem. QSM has become sufficiently accurate and robust for routine applications. QSM is advancing MRI study of tissue magnetic susceptibility from simple qualitative detection of its hypointense blooming artifacts to precise measurement of its biodistributions.
Bio: Yi Wang (PhD 1994, University of Wisconsin-Madison) is the Faculty Distinguished Professor of Radiology, professor of Biomedical Engineering, and Director of MRI Research Institute at Cornell University. Prof. Wang has been developing MRI+ technology to enable precision medicine, using physics modeling and computation tools guided by biological knowledge. His work includes quantitative susceptibility mapping (QSM) and quantitative transport mapping (QTM).