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"Synaptic dysfuntion caused by tau mislocalization in neurodegenerative diseases ," by Dezhi Liao, Ph.D., Professor, Department of Neuroscience, The University of Minnesota

Event Type
Seminar/Symposium
Sponsor
Neuroscience Program
Location
Beckman Institute 1005
Date
Apr 26, 2022   4:00 pm  
Speaker
Dezhi Liao, University of Minnesota
Contact
Neuroscience Program
E-Mail
nsp@life.illinois.edu
Phone
217-300-7978
Views
80
Originating Calendar
Neuroscience Program Seminars

Increasing evidence supports a key role of tau in mediating synaptic and cognitive dysfunction in Alzheimer’s disease and other neurodegenerative diseases.  The seminar will introduce a common mechanism underlying these diseases: the redistribution of microtubule associated protein tau (MAPT) from the axon into the somatodendritic compartments of neurons and further into dendritic spines, causing loss of AMPA receptors in spines.  

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