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"Differential Resilience to Perturbations of Circuits with Similar Performance" by Eve Marder, Ph.D. Victor and Gwendolyn Beinfield University Professor, Brandeis University

Event Type
Seminar/Symposium
Sponsor
Neuroscience Program
Date
Sep 1, 2020   4:00 pm  
Speaker
Eve Marder, Ph.D., Brandeis University
Contact
Gene Robinson; Tish Cundiff
E-Mail
generobi@illinois.edu; lcundiff@illinois.edu
Views
40
Originating Calendar
Neuroscience Program Seminars

Both computational and experimental results in single neurons and small networks demonstrate that very similar network function can result from quite disparate sets of neuronal and network parameters. Using the crustacean stomatogastric nervous system, we now study the influence of these differences in underlying structure on differential resilience of individuals to a variety of environmental perturbations, including changes in temperature, pH, potassium concentration and neuromodulation. We show that neurons with many different kinds of ion channels can smoothly move through different mechanisms in generating their activity patterns, thus extending their dynamic range.

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