17 matches found
Oxytocin is often considered to be a peptide that is important for behaviors related to social approach such as pair bonding or stress buffering. However, sometimes oxytocin can increase anxiety. Our work shows that these diverse effects are mediated by distinct but overlapping neural circuits.
Christian-Hinman will describe recent work from her lab exploring these issues in a mouse model that recapitulates critical features of human temporal lobe epilepsy. Their investigations span from single-cell electrophysiological measurements of neuronal activity, excitability, & synaptic signaling to whole-animal assays of female reproductive cyclicity & seizure activity.
There is growing evidence that puberty is another organizational period with long lasting effects on brain and behavior. This talk will provide an overview of human structural MRI studies on sex differences in normative brain development across adolescence. Evidence for a specific link between pubertal maturation and developmental changes will be discussed.