Neuroscience Program Seminars
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From birth to adulthood, an animal’s nervous system undergoes considerable expansion. Through serial electron microscopy and functional imaging studies, we reveal several developmental principles that govern the structural growth and functional maturation across the wiring diagram of C. elegans.
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Reproduction is governed by the coordinated secretion of hormones from the brain & pituitary. The hormones, GnRH & LH, are released in discrete "pulses", whose unique pattern is regulated by many factors. Mechanisms by which endocrine & neural signals modulate reproductive hormone pulses in normal & disease states will be discussed, focusing on findings from mouse models.
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Martha Gillette presented in a paper in 1987, "Oscillations in VP secretion and neuronal firing rate potentially represent separate modes by which the SCN transmit time information to other brain regions. The electrical oscillation may relay time-of-day by efferent neuronal output along a limited number of specialized circuits..."