Neuroscience Program

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"Long-range inhibitory neurons expressing Tacr1 are strong regulators of cerebral blood flow," by Alberto Vazquez, Associate Professor of Radiology and Bioengineering, Member of the Center for Neuroscience and the Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA

Event Type
Seminar/Symposium
Sponsor
Neuroscience Program
Location
Beckman Institute 1005
Date
Nov 12, 2024   4:00 pm  
Contact
Xinzhu Yu
E-Mail
xinzhuyu@illinois.edu
Views
28
Originating Calendar
Neuroscience Program Seminars

The brain dynamically regulates its blood supply presumably to meet neuronal metabolic demands. We identified a sparse, long-projecting population of inhibitory neurons expressing NOS and Tachykinin receptor 1 (Tacr1) that strongly regulate cerebral blood flow. They respond to excitatory feed-forward input and their processes come in close contact with astrocytic end-feet and blood vessels, suggesting that Tacr1 neurons integrate cortical activity to regulate blood supply.

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