Dr. Edward Cooper, Baylor College of Medicine, "Why are KCNQ2 Phenotypes so diverse? Insights from patients, new structures, and mice"
- Event Type
- Seminar/Symposium
- Sponsor
- MIP Seminar Committee
- Location
- Charles Miller Auditorium, B102, CLSL
- Date
- Sep 26, 2024 11:00 am
- Speaker
- Edward Cooper, M.D., Ph.D.
- Contact
- Julie Moore
- jmoor@illinois.edu
- Views
- 174
- Originating Calendar
- Molecular and Integrative Physiology (MIP) Department Seminar Series
"Why are KCNQ2 Phenotypes so diverse? Insights from patients, new structures, and mice"
The major focus of our work is forms of human epilepsy arising from mutations in voltage-gated sodium and potassium channels. We discovered that KCNQ potassium channels were concentrated in the axon, and identified the first molecular mechanisms for KCNQ channel targeting at the axonal initial segment and nodes of Ranvier.