"Blood-brain barrier permeability contributes to cognitive impairment in a mouse model of Long COVID," by Sarah Elizabeth Lutz, PhD, Assistant Professor of Anatomy and Cell Biology, Associate Director of the Center for Cardiovascular Research, University of Illinois Chicago
- Event Type
- Seminar/Symposium
- Sponsor
- Neuroscience Program
- Location
- Beckman Institute 1005
- Date
- Oct 15, 2024 4:00 pm
- Contact
- Andrew Steelman
- asteelma@illinois.edu
- Views
- 162
- Originating Calendar
- Neuroscience Program Seminars
Many individuals experience long-lasting cognitive/neurological problems after COVID-19, but the causes are unknown. We find that cerebrovascular Wnt/beta-catenin pathway suppression contributes to neuroinflammation and cognitive deficits in COVID-19/Long COVID mouse models by opening transcellular and paracellular blood-brain permeability. This suggests potential therapeutic strategy.