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The next C3.ai Digital Transformation Institute Colloquium on Digital Transformation Science Webinar will be Thursday, January 28 at 3:00 p.m. U.S. Central time. The talk, "Modeling and Managing the Spread of COVID-19," will be presented by Subhonmesh Bose from the University of Illinois at Urbana-Champaign. Registration is required to attend this event.
Abstract: Testing and lock-down provide two important control levers to combat the spread of an infectious disease. Testing is a targeted instrument that permits the isolation of infectious individuals. Lock-down, on the other hand, is blunt and restricts the mobility of all people. In the first part of the talk, I will present a compartmental epidemic model that accounts for asymptomatic disease transmission, the impact of lock-down and different kinds of testing, motivated by the nature of the ongoing COVID-19 outbreak. In the large population regime, static mobility levels and testing requirements are characteristics that can mitigate the disease spread asymptotically. Then, I present interesting properties of an optimal dynamic lock-down and testing strategy that minimizes a detailed cost of the epidemic. In the second part of the talk, I adapt the model for small populations, such as that of an educational institution, and use data from the UIUC SHIELD program’s rapid saliva-based testing strategy to estimate model parameters. Reopening strategies for educational institutions are evaluated via agent-based simulations using said parameter estimates. This talk is based on joint work with U. Mukherjee, S. Seshadri, S. Souyris, A. Ivanov, Y. Xu, and R. Watkins.