Super-Resolution via Image Inversion Interferometry using Polarization Selection
Abstract: Resolving two incoherent sources of light is an important issue in single molecule spectroscopy. Direct imaging at small scales becomes increasingly more difficult due to Rayleigh’s criterion, so creating imaging techniques to resolve images below this limit is desirable. One of these promising super-resolution techniques is image inversion interferometry (III) which allows for resolution below the diffraction limit by separating and analyzing the even and odd Hermite-Gaussian (HG) modes of light. This technique allows for superresolution without the need for stochastic blinking or photoswitching off nearby sources unlike other techniques that can limit the range of labeling conditions. For this new technique to work properly, only the light with symmetry should pass into the interferometer which can be done by selecting for only the azimuthal polarization.
Student Bio: Cheyenne Mitchell is a 5th year chemistry graduate student working for Dr. Mikael Backlund and researching super-resolution single molecule microscopy.