The growth and evolution of galaxies over cosmic time is regulated by complex interplay of intergalactic accretion on large scales and feedback energy injected by star formation and blackholes on small scales. All simulations that (even marginally) resolve the interstellar medium and include stellar feedback agree that the winds driven out of galaxies are expected to be highly multiphase. Most of the mass is carried by the clumpier, cooler ~10^4 K gas and most of the energy is carried by the hotter >~ 10^6 K, more volume filling gas. As these two phases flow out of the galaxy they interact with each other, exchanging mass, momentum, and energy. This exchange is mediated by the competition between turbulent mixing and radiative cooling in the layers that separate the phases. I will review these processes, highlighting the impact they have on observable properties, and then introduce a new model---Arkenstone---that enables us to explicitly include these phenomena and to reliably model multiphase galactic winds in large global/cosmological simulations. I will wrap up with a discussion of the broad implications and introduce an intuitive picture for how these winds and their interaction with the CGM regulate galaxy growth over cosmic history.