The Willard J. and Priscilla F. Visek Lecture: David Moore
- Event Type
- Seminar/Symposium
- Sponsor
- College of Agricultural, Consumer and Environmental Sciences Division of Nutritional Sciences
- Location
- Beckman Institute Room 1025-Auditorium
- Date
- Oct 12, 2022 4:00 pm
- Speaker
- David Moore, Professor and chair, Department of Nutritional Sciences & Toxicology, University of California Berkeley, Berkeley, California.
- Contact
- Angela Dean
- aedean2@illinois.edu
- Views
- 117
- Originating Calendar
- Beckman and Campus Calendars
Title: "Regulation of liver energy balance by nutrient sensing nuclear receptors"
Speaker: David Moore, Professor and chair, Department of Nutritional Sciences & Toxicology, University of California Berkeley, Berkeley, California.
The liver is crucial for maintaining whole body energy balance. For example, it responds to fasting by secreting glucose and to feeding by both metabolizing it and storing it as glycogen. The nuclear receptors FXR and PPARα are activated in the fed or fasted liver, respectively, and regulate many basic metabolic processes. Dr. Moore's lab have found that both receptors also regulate processes that are not directly related to metabolic pathways but are central to liver energy balance. Dr. Moore's presentation will focus on the previously described roles of FXR and PPARα in control of autophagy and more recent results on control of the liver secretome.