Urbana Campus Research Calendar

Back to Listing

"CNS regulation of spontaneous physical activity in animal models and the impact on obesity resistance" by Catherine M. Kotz, PhD, FTOS, Professor and Director of Graduate Studies, Integrative Biology and Physiology, University of Minnesota

Event Type
Lecture
Topics
obesity therapies, orexin therapeutic interventions, spontaneous physical activity
Sponsor
Neuroscience Program
Location
Beckman 1005
Date
Jan 29, 2019   4:00 pm  
Speaker
Catherine M. Kotz, PhD, FTOS, University of Minnesota
Contact
Nu-Chu Liang
E-Mail
ncliang8@illinois.edu
Views
29
Originating Calendar
Neuroscience Program Seminars

Spontaneous physical activity (SPA) behavior, or the drive to move, is initiated by brain centers and could therefore be therapeutically targeted. A major goal of our work is to understand the brain circuitry driving SPA, so that obesity therapies based on SPA can be considered. The neuropeptide orexin is part of the circuitry driving SPA. I will discuss our work using animal models to study the impact of orexin loss and gain, as well as natural variation in SPA, I will also present work on proof of concept studies for orexin therapeutic interventions for obesity using chemogenetics for orexin.

link for robots only