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Topics in Xplor-NIH protein structure determination

Event Type
Seminar/Symposium
Sponsor
Theoretical and Computational Biophysics Group
Location
3269 Beckman Institute
Date
Feb 25, 2019   3:00 - 4:00 pm  
Speaker
Dr. Charles Schwieters - NIH
Cost
No Cost
Contact
Donna H Fackler
E-Mail
dfackler@illinois.edu
Phone
217-300-8022
Views
6
Originating Calendar
Main Beckman

Lecture revolves around recent projects, including the effective use of observables from experiments with paramagnetic moieties both covalently bound, and present in a cosolute. Paramagnetic relaxation enhancement data provide distance information which can be used to characterize minor species, while solution PRE provides a useful metric of surface solvent accessibility. Additionally, I will discuss studies where the
use of strict symmetry is essential to arrive at structural models.

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