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Shulei Wang

STC for Quantitative Cell Biology / Biological Physics (iPoLS) Seminar: Glenn Fried

Event Type
Seminar/Symposium
Sponsor
NSF Science and Technology Center for Quantitative Cell Biology
Location
Beckman Institute Room 3269 (3rd Floor Tower Room)
Date
Nov 13, 2023   1:30 pm  
Speaker
Glenn Fried, Institute of Genomic Biology, UIUC.
Contact
Sharlene Denos
E-Mail
denos@illinois.edu
Views
15
Originating Calendar
Beckman and Campus Calendars

Glenn Fried, Institute of Genomic Biology, UIUC, will lecture on "Cell imaging to the 2nm scale in the IGB Core."

The IGB Core has grown to provide a large array of state of the art imaging tools to elucidate spatial order in biological systems. 

This talk will cover both the workhorse tools such as confocal, slide scanners and tissue imaging tools as well as the new MINFLUX microscope and future capabilities such as sequential FISH and volume EM. The MINFLUX purchased in partnership with the Quantitative Cell Biology STC provides 2nm resolution with a smaller photon budget than other comparable super resolution instruments.  Sequential FISH imaging provides the ability to localize tens to hundreds of different mRNA with sub cellular resolution while volume EM locates all cellular substructures to 25nm resolution. The combination of these tools will provide an understanding of subcellular process with unprecedented resolution and specificity.

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