The protein databases contain an exponentially growing number of sequences as a result of the recent increase in ease and decrease in cost of genome sequencing. The rate of data accumulation far exceeds the rate of functional studies, producing an increase in genomic 'dark matter,' sequences for which no precise and validated function is defined. Join the Enzyme Function Initiative (EFI) at the IGB to learn how to use the tools they developed to identify, explore, and leverage the protein and genome databases for discovery of the in vitro activities and in vivo functions of novel enzymes and proteins belonging to the 'dark matter.'
