Cortical layer specific functional MRI at ultra-high field, Jozien Goense, Associate Professor of Psychology and Bioengineering at Illinois, will lecture on “Cortical layer specific functional MRI at ultra-high field” at 4:00 pm April 5 in 2269 Beckman Institute and on Zoom. MBM trainee and PhD candidate, Charles Marchini, will give an introduction.
The lecture is free and open to the public courtesy of the Miniature Brain Machinery Program.
Bio:
Jozien Goense recently joined the faculty of Psychology and Bioengineering at Illinois in Fall 2022. Before that, she was teaching at the University of Glasgow in Scotland. Her research focuses on investigating the laminar neural circuits in the sensory cortex of humans and animals as well as elucidating the relationship between neural activity and hemodynamic response using high-resolution fMRI at ultra-high field and multi-channel electrophysiology.
Abstract:
To understand brain function it is important to gain a better understanding of the functional units of the cortex, i.e., its columns and layers. High-resolution fMRI has tremendous potential for the study of cortical circuits in vivo and in recent years there is an increasing interest in studying laminar circuits using ultra high field (7T) fMRI. However, questions remain about the size of cortical features that can be resolved and how the fMRI signals relate to the underlying neural activity (neurovascular coupling). We use high-resolution fMRI and multichannel electrophysiology to gain insight into the layer-dependent fMRI- and neural responses, and neurovascular coupling mechanisms. I will discuss our fMRI- and electrophysiology work in the macaque primary visual cortex and sensorimotor cortex in humans and rats. We exploit the well-studied layered structure of primary sensory and motor cortex to investigate laminar differences in BOLD, cerebral blood flow (CBF) and cerebral blood volume (CBV) in response to excitatory and inhibitory stimuli, and to determine their relation to the neural signals.
Learn More (ResearchGate) >>
Join Zoom Meeting
https://illinois.zoom.us/j/84731354504?pwd=UWVJaDFIOXVUZFJFSE4xWUJJMlZmUT09
Meeting ID: 847 3135 4504
Password: 132372
