"Biomaterials to Enhance T Cell Cancer Therapies"
T cell-based therapies are revolutionizing the treatment of some types of cancer, but currently suffer from a number of limitations. To address these challenges, we are developing biomaterials capable of concentrating, interrogating, and manipulating stem and immune cells ex vivo and in the body by controlling, in space and time, the interaction of the cells with various immunomodulatory cues. The development of artificial antigen presenting cells for the manufacturing and in vivo boosting of adaptive T cell-based therapies will be highlighted.
