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Advances in synthetic biology and protein engineering have dramatically expanded our capabilities for tailoring biomolecular chemistry and materials in human-engineered technologies. Realizing this potential will require breakthroughs in high-throughput characterization to rapidly and efficiently screen the vast chemical and formulation design spaces opened by these new capabilities. Although high-throughput screening has long been implemented in biochemical characterization, methods for high-throughput thermomechanical characterization of materials have lagged significantly behind. Based on optical observation and analysis of Brownian motion in a test material, microrheology holds significant potential to fill this gap for informing rheological design of scarce, multi-phase or time-evolving materials.
