Abstract: This talk will cover recent discoveries regarding the range of phase transitions that
RNA binding proteins can undergo in vitro and in cells. The growing corpus of data shows that
RNA binding proteins can form microphases, clusters that undergo percolation, macrophases,
and everything in between. Long non-coding RNAs modulate the phase transitions of RNA
binding proteins in RNA-specific ways. The implications for phase transitions in cell biology and
the functions of specific nuclear bodies such as nuclear speckles will be discussed. The talk will
strive to bridge the fields of biophysics, computations, biochemistry, and cell biology.