UIUC Biophysics and Related Seminars

View Full Calendar

Dr. Mitchell Roitman, University of Illinois at Chicago, "The mesolimbic dopamine system in the homeostasis-to-action arc"

Event Type
Seminar/Symposium
Sponsor
MIP Seminar Committee
Location
Charles Miller Auditorium, B102, CLSL
Date
Nov 2, 2023   11:00 am  
Speaker
Mitchell Roitman, Ph.D.
Contact
Julie Moore
E-Mail
jmoor@illinois.edu
Views
34
Originating Calendar
Molecular and Integrative Physiology (MIP) Department Seminar Series
"The mesolimbic dopamine system in the homeostasis-to-action arc"

Roitman lab is interested in determining the neural basis of adaptive (feeding and drinking) and maladaptive (over-eating, drug-taking) motivated behaviors. We are particularly interested in the role of the mesolimbic dopamine system. The nucleus accumbens and the neurotransmitter dopamine are critical brain substrates involved in motivated behavior including feeding and drug-taking. They appear to be vital to reward-related learning as well. Since the nucleus accumbens accesses motor-related structures it is well suited to modulate behavior based on changes in motivational state and learned associations. Our research seeks to determine how this system integrates information about valence (reward vs. aversion) with peripheral and central signals that convey information about physiological state (e.g. hunger, thirst, satiety, drug-withdrawal). We also seek to determine whether modulation of these signals can resolve aberrant processing that underlie maladaptive behavioral responses. To accomplish this, we employ state-of-the-art recording techniques and virally-delivered construct for circuit manipulations with detailed behavioral analyses. Our program of research will shed considerable light on human disorders of motivation such as obesity and drug-addiction. 
http://mroitman.wix.com/mroitman 

Please contact the UIUC Illinois Biophysics Society webmaster if you know of other events to add to the list.

link for robots only