Cancer Center Master Calendar
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After an amazing and fun time last year, the Prairie Dragon Paddlers’ annual fundraising event is back to raise money to support breast cancer survivorship and research in our community. It’s an evening of live entertainment from our 10 finalist singers who YOU VOTE FOR with your dollars–plus great food, cash bar and special guest performances!
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The Cancer Center at Illinois is pleased to present the Faculty Seminar Series. Each session includes brief individual talks from a group of faculty members followed by a Q&A period. Registration is encouraged but not required for attendance.
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Organized by the TiMe graduate student cohort, the third annual TiMe Day Symposium on April 26, 2019, will highlight research from the program, include keynote and plenary talks, and culminate with a poster session in which all graduate and undergraduate students are encouraged to present their work.
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Development of multi-organ microphysiological platforms for drug testing
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Composed of individuals who have been diagnosed with cancer or have a strong personal connection to it, CRAG promotes interactions between cancer survivors, researchers, and clinicians that are essential in the fight against cancer and lead to better outcomes for all.
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The Illini 4000 is a non-profit organization dedicated to documenting the American cancer experience through The Portraits Project, raising funds for cancer research and patient support services, as well as spreading awareness for the fight against cancer through annual cross-country bike rides.
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This Wednesday at 12 pm in 2310 Everitt is the Bioengineering Graduate Student Seminar. This year, two students, Aidan Brougham-Cook (Greg Underhill) and Samantha Zambuto (Brendan Harley), will present their research. We encourage all faculty to attend this seminar and support our graduate students and the graduate program.
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Adipose tissue plays a fundamental role in systemic metabolism. Aberrant adipose tissue function contributes to excess morbidity and mortality, with obesity alone generating a greater than $190 billion burden annually on the American healthcare system. The negative effects of obesity may outweigh the positive effects of smoking cessation on the overall health of the US pop
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Current crop models predict an increasing gap between food supply and demand over the next 50 years. Technology is needed to predict the fitness of existing germplasm in response to global change, and also to design of crop ideotypes. I will highlight our efforts to generate virtual plant models that capture whole system dynamics in response to in silico environmental and
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Crosstalk of Adhesion Complexes and the RNAi Machinery in Epithelial Homeostasis and Cancer Panagiotis Anastasiadis, PhD Professor of Cancer Biology Department Chair Mayo Clinic Cancer Center
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The metastatic spread of tumors to distant organs is responsible for more than 90% of cancer-related deaths. Malignant cells that detach from a primary tumor and spread through the bloodstream are called circulating tumor cells (CTCs). Analysis of CTCs collected from blood holds promise as a repeatable and minimally invasive alternative for tissue biopsies. However, widesp
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Antibodies act as a nexus between innate and adaptive immunity: they provide a means to target the potent toxic activities of a spectrum of innate immune effector cells in order to clear viral particles and infected cells. This functional landscape is remarkably complex, with multiple antibody variants directed to multiple epitopes on multiple viral antigens. This diversit
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Dr. Miller will discuss results from his study of pre-clinical Alzhimer's disease as part of the BIOCARD project. We will examine the central technologies of Computational Anatomy based on diffeomorphometry for quantifying the anatomical structures of 3T clinical MRI at 1 millimeter scale.
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Microbial strains have been successfully engineered to produce a wide variety of chemical compounds, several of which have been commercialized. As new products are targeted for biological synthesis, yield is frequently considered a primary driver towards determining feasibility. Theoretical yields can be calculated, establishing an upper limit on the potential conversion
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BIOE Seminar - Dr. Elsje Pienaar - Computational Agent-Based and Equation-Based Models of TB and HIV
TB and HIV are the leading causes of death from infectious diseases in the world, causing a combined 12 million new infections each year. They are also a deadly combination in co-infected patients, and as many as 70% of TB patients are co-infected with HIV. Both infections require long-term, multi-drug therapy and suffer from emergence of drug resistance. Thus, there is a
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There are currently no effective approaches to treat presbyopia, the unavoidable age-related loss of the ability of the eye to accommodate (i.e., to change focus). Most of the current strategies for the correction of presbyopia rely on the assumption that presbyopia is due mainly to age-related changes in the mechanical properties of the crystalline lens of the eye. Howeve
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Abstract: The fact that the most significant life-threatening diseases of our times such as Cardiovascular Diseases or Cancer remains the number one killer for over a century suggests that, despite the advancements in science and medicine over the years, there is a huge gap in translating these scientific findings to clinical setting. One of the major reasons for this gap
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Understanding how cells probe, interpret, and respond to the extracellular matrix is critical to tissue engineering and disease modeling efforts. While our knowledge of cellular mechanosensing of elastic hydrogel surfaces has recently grown rapidly, less is known about this process in the context of networks of fibrous proteins such as type I collagen that comprise stromal
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By stimulating or recording electrical activity, microelectrode arrays implanted in the brain have created a renaissance in the treatment of neurological diseases and injuries. Likewise, these devices are an enabling technology to understand normal brain function and behavior. However, questions remain regarding the relationship between the biological response to implanted
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By physically combining electromagnetic and ultrasonic waves, photoacoustic imaging (PAI) has proven powerful for multi-scale anatomical, functional, and molecular imaging. In PAI, a short-pulsed laser beam illuminates the biological tissue to generate a small but rapid temperature rise, which leads to emission of ultrasonic waves due to thermoelastic expansion. The high-
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Following traumatic injury to the adult central nervous system (CNS), neural connectivity is lost and fails to spontaneously regrow. This regeneration failure may be due to an intrinsic inability for damaged neurons to regrow in the adult as well as the formation, and persistence, of a lesion that is devoid of essential axon growth cues. My work is focused on using bioengi
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We have previously developed an implanted neuroprosthesis that uses functional electrical stimulation (FES) to activate the paralyzed muscles of the shoulder, arm, and hand in a coordinated manner to restore arm and hand function, and successfully deployed this system in three people with severe paralysis. We have more recently developed and deployed a FES system for the
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From microbes to cancer, variability in gene expression can lead to nongenetic phenotypic heterogeneity. This heterogeneity is important in determining how populations of cells grow, survive fluctuating environments, and develop drug resistance. For example, individual yeast cells within isogenic populations show striking heterogeneity in stress tolerance. Though genetic f
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Incorporating diverse molecular and cellular signaling processes into integrated, organismic-scale models of brain function is a formidable challenge for modern neuroscience. Molecular functional magnetic resonance imaging (fMRI) is a new technology that can bridge the molecular and cellular precision with whole-brain coverage in intact living animals. Here I will present
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BIOE Seminar - Dr. Joseph Culver - Developing Neurophotonics for Mapping Distributed Brain Functions
Diffuse optical tomography (DOT), is a technology that uses light from outside the head to track what the brain is doing. Optical imaging avoids the radiation exposure and bulky magnets other brain imaging technologies require. The approach is particularly useful for studying children and people with cochlear implants, pacemakers, deep brain stimulators and other implants
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AgBiome leverages a vast collection of microbes to discover crop-protective products. We are continually refining the use of genomics to make our screening and discovery strategies more effective. We recently completed a discovery program for bacterial isolates with fungicidal activity against Colletotrichum, the causative agent of a devastating plant disease called Sorghu
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The CCIL is excited to host John Cheville, Professor of Pathology and Consultant at Mayo Clinic, as our first Faculty Seminar Series guest in 2020. Cheville is an expert on urologic cancers and their pathologies.
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Advancing diversity and inclusion have been persistent challenges in STEM. Consequently, there remains an urgent need for interventions addressing the needs of marginalized students as they progress through undergraduate degree programs. To support this effort, Dr. Walter Lee’s research focuses on better understanding the interventions (program, activities, and services)
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Significant advances in directed evolution have allowed for the exploration of many new and important non-natural transformations; however, many of these ground-breaking reactions still rely on the use of low-throughput chromatography-based methods to sift through variants. To remove this limitation, we adopted a high-throughput screening strategy to evaluate libraries of
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CCIL Director Rohit Bhargava will provide a summary of the feedback of our NCI cancer center designation grant (CCSG) submission. There will also be an introduction of the Cancer Center’s five-year strategic plan initiative.
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Mechanical engineering professor Mariana Kersh presents her research on musculoskeletal health
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Chemical engineering professor Diwakar Shukla presents on computation structural biology of plants.
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Biomedical engineering professor Casey Ankeny presents strategies for in-person and remote teaching
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Bioengineering professor Paul Jensen presents his research on Streptococcus sobrinus and tooth decay
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Bioengineering professor Andrew Smith presents his research on nanoparticles for molecular imaging
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The Cancer Center at Illinois invites Illinois researchers to attend a virtual Shared Resources Town Hall. Presentations by Joseph Irudayaraj, CCIL Associate Director for Shared Resources, and Hui Xu, Research Coordinator for the Tumor Engineering and Phenotyping (TEP) lab.
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CCIL Fall 2020 Seminar Speakers: Rohit Bhargava, PhD CCIL Director and Founder Professor in Engineering "Chemical Imaging for Cancer Pathology" Zeynep Madak-Erdogan, PhD CCIL Member and Associate Professor, Food Science & Human Nutrition "Modulation of Cancer Metabolism by Metastatic Tissue Microenvironment and Drugs in Metastatic ER+ Breast Cancer"
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CCIL Fall 2020 Seminar Speakers:
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Dr. Elizabeth Salerno, Assistant Professor, Washington University School of Medicine, will highlight the unique health challenges of accelerated aging after cancer and how physical activity may be leveraged to improve functional health during survivorship.
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3D and 4D Computational Imaging of Molecular Orientation with Multiview Polarized Fluorescence Microscopy