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Biomimetic Synthesis of Calcium Phosphate-based Bone Substitutes

Event Type
Other
Topic
graduate
Sponsor
MechSE
Location
2005 Mechanical Engineering Laboratory (Deere Pavilion)
Date
Sep 30, 2013   12:00 pm  
Speaker
Dr. A. Cuneyt Tas, Materials Science and Engineering, University of Illinois at Urbana-Champaign
Views
1092

Biomimetic synthesis of bone substitutes shall be performed in aqueous media similar in composition to that of blood, and such synthesis media shall not contain any man-made organic chemicals which are not native to the human metabolism. Inorganic ions (such as Ca2+, Mg2+, Na+, K+, HCO3-, HPO42-) present in blood are also present in the nanocrystals of hard tissues. Biomimetic syntheses performed in synthetic biomineralization media at 37°C resulted in ion-doped CaP nanopowders of high BET surface areas from 220 to 900 m2/g.

This presentation will summarize our efforts towards developing new biomineralization media (BM-3, BM-7, Lac-SBF and alike) and the biomimetic synthesis of non-stoichiometric and ion-substituted calcium phosphate- and calcium carbonate-based bone substitute materials in the form of coatings or aqueous pastes also having the potential of use in drug delivery applications.

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